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  5. Tocris Bioscience™ PFI 4

Tocris Bioscience™ PFI 4

Catalog No. 557650
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50 mg
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557650 50 mg
557610 10 mg
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Catalog No. 557650 Supplier Tocris Bioscience™ Supplier No. 5576/50
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Description

Potent and selective BRPF1 bromodomain inhibitor

PFI 4 is a potent and selective BRPF1B bromodomain inhibitor (IC50 = 172 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. Disrupts BRPF1 binding to histone H3.3. Cell permeable. Inhibits osteoclastogenesis.

Specifications

Chemical Name or Material PFI 4
CAS 900305-37-5
Synonym N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide
Quantity 50 mg
Solubility Soluble to 50mM in DMSO and to 10mM in ethanol
Molecular Formula C21H24N4O3
Formula Weight 380.44
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >99%

Research Use Only. Not For Human or Veterinary Use

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