R&D Systems PFI 4, Tocris™

Potent and selective BRPF1 bromodomain inhibitor

Manufacturer: R&D Systems 5576/50

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Catalog No. 557650

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Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material PFI 4
    CAS 900305-37-5
    Assay Percent Range >99%
    Molecular Formula C21H24N4O3
    Formula Weight 380.44
    Synonym N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide
    Recommended Storage Store at +4°C.
    Quantity 50mg
    Solubility Soluble to 50mM in DMSO and to 10mM in ethanol
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4
    • Disrupts BRPF1 binding to histone H3.3
    • Cell permeable

  • Description & Specifications

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