R&D Systems PFK 15, Tocris™

Selective PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor

Manufacturer: R&D Systems 5339/10

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Catalog No. 533910

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Research Use Only. Not For Human or Veterinary Use


    Physical Form Solid,Solid
    Chemical Name or Material PFK 15
    Product Type Bioactive Small Molecules
    Synonym 1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
    Recommended Storage Store at -20°C.
    Solubility Soluble to 100mM in DMSO
    CAS 4382-63-2
    Assay Percent Range >99%
    Molecular Formula C17H12N2O
    Formula Weight 260.29
    Quantity 10mg

    • Selective for PFKFB3 over a panel of 96 other kinases
    • Reduces glucose uptake and induces apoptosis in H522 lung adenocarcinoma and Jurkat T cell leukemia cells
    • Suppresses glucose uptake and tumor growth, and inhibits lung metastasis of Lewis lung carcinoma cell xenografts in mice

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