R&D Systems PR 619, Tocris™

Broad spectrum, reversible DUB inhibitor

Manufacturer: R&D Systems 4482/50

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Catalog No. 448250

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Disclaimers:

Research Use Only. Not For Human or Veterinary Use


    Specifications

    Chemical Name or Material PR 619
    CAS 2645-32-1
    Assay Percent Range >98%
    Molecular Formula C7H5N5S2
    Formula Weight 223.28
    Synonym 2,6-Diamino-3,5-dithiocyanopyridine
    Recommended Storage Store at -20°C.
    Quantity 50mg
    Solubility Soluble to 10mM in DMSO
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Exhibits limited activity against other proteases. Induces accumulation of polyubiquitinated proteins, but has no direct inhibitory effect on the proteasome
    • Cytotoxic in HEK293T and colorectal cancer cells
    • Stabilizes microtubule network in oligodendroglial cells

  • Description & Specifications

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