Tocris Bioscience™ QAQ Dichloride
Photoswitchable Nav, Kv and Cav channel blocker
Manufacturer: Tocris Bioscience™ 5470/50
DescriptionQAQ dichloride is a photoswitchable Nav, Cav and Kv channel blocker. Blocks channels in the trans conformation. Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. Normally membrane impermeant, but enters nociceptive neurons via ion channels activated by noxious stimuli, particularly TRPV1. Exhibits optically reversible local anesthesia in rats.
|Non-selective Cav Blockers|
|Bioactive Small Molecule|
|Soluble to 50mM in water|
Safety and Handling
Recommended Storage : Store at -20°C
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Research Use Only. Not For Human or Veterinary Use