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Tocris Bioscience™ QAQ Dichloride

Photoswitchable Nav, Kv and Cav channel blocker

Manufacturer:  Tocris Bioscience™ 5470/50

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Catalog No. 547050


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Description

Description

QAQ dichloride is a photoswitchable Nav, Cav and Kv channel blocker. Blocks channels in the trans conformation. Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. Normally membrane impermeant, but enters nociceptive neurons via ion channels activated by noxious stimuli, particularly TRPV1. Exhibits optically reversible local anesthesia in rats.
Specifications

Specifications

Non-selective Cav Blockers
C28H44Cl2N6O2
Bioactive Small Molecule
QAQ dichloride
50 mg
567.59
Solid
>98%
2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride
Soluble to 50mM in water
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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Research Use Only. Not For Human or Veterinary Use