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  5. Tocris Bioscience™ Ro 1138452 Hydrochloride

Tocris Bioscience™ Ro 1138452 Hydrochloride

Catalog No. 426810
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Catalog No. 426810 Supplier Tocris Bioscience™ Supplier No. 4268/10
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Description

Selective prostacyclin IP receptor antagonist

Ro 1138452 hydrochloride is a selective prostacyclin IP receptor antagonist (pKi = 8.3). Exhibits no affinity at other prostanoid receptors (EP1-4, FP and TP) in a radioligand binding assay. Demonstrates analgesic activity in rats. Orally bioavailable.

Specifications

Chemical Name or Material Ro 1138452 hydrochloride
Synonym 4,5-Dihydro-N-[4-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-1H-imidazol-2-amine hydrochloride
Quantity 10 mg
Solubility Soluble to 100mM in water and to 100mM in DMSO
Molecular Formula C19H23N3O·HCl
Formula Weight 345.87
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use

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