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  5. Tocris Bioscience™ TC-G 1005

Tocris Bioscience™ TC-G 1005
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Catalog No. 512910
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Catalog No. 512910 Supplier Tocris Bioscience™ Supplier No. 5129/10
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Description

Potent and selective GPBA receptor (TGR5) agonist

TC-G 1005 is a potent and selective GPBA agonist (EC50 values are 0.72 nM and 6.2 nM for hTGR5 and mTGR5, respectively). TC-G 1005 is selective for TGR5 over FXR (farnesoid X receptor). TC-G 1005 increases plasma GLP-1 levels and reduces blood glucose in mice. Orally bioavailable.

Specifications

Chemical Name or Material TC-G 1005
CAS 1415407-60-1
Synonym (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 100mM in ethanol
Molecular Formula C25H25N3O2
Formula Weight 399.48
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use

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