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Tocris Bioscience™ TC-I 2014
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Catalog No. 541010
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Catalog No. 541010 Supplier Tocris Bioscience™ Supplier No. 5410/10
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Description

Potent TRPM8 antagonist

TC-I 2014 is a potent TRPM8 antagonist (IC50 values are 0.8, 3.0 and 4.4 nM for canine, human and rat channels respectively). Exhibits antiallodynic properties in pain models in vivo.

Specifications

Chemical Name or Material TC-I 2014
CAS 1221349-53-6
Synonym 3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene
Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 100mM in ethanol
Molecular Formula C23H19F6N3O
Formula Weight 467.41
Physical Form Powder
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use

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