R&D Systems VU 0422288, Tocris™

Group III mGlu receptor positive allosteric modulator

Manufacturer: R&D Systems 5378/10

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Catalog No. 537810

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Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material VU 0422288
    CAS 1630936-95-6
    Assay Percent Range >98%
    Molecular Formula C17H11Cl2N3O2
    Formula Weight 360.19
    Synonym N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide
    Recommended Storage Store at +4°C.
    Quantity 10mg
    Solubility Soluble to 100mM in DMSO
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Exhibits selectivity over a panel of 68 other GPCRs, ion channels and transporters
    • Potentiates mGlu7-mediated reductions in excitatory post synaptic potentials in hippocampal slices

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