R&D Systems VU 0469650 Hydrochloride, Tocris™

Potent and selective negative allosteric modulator of mGlu1

Manufacturer: R&D Systems 5379/10

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Catalog No. 537910

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Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material VU 0469650 hydrochloride
    CAS 1443748-47-7
    Assay Percent Range >98%
    Molecular Formula C22H28N4O·HCl
    Formula Weight 400.94
    Synonym 3-[(3R)-3-Methyl-4-(tricyclo[,7]dec-1-ylcarbonyl)-1-piperazinyl]-2-pyridinecarbonitrile hydrochloride
    Recommended Storage Store at +4°C.
    Quantity 10mg
    Solubility Soluble to 100mM in DMSO and to 50mM in ethanol
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Exhibits >100-fold selectivity for mGlu1 over mGlu2-8 and 68 other GPCRs, ion channels, kinases and transporters
    • Brain penetrant

  • Description & Specifications

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