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Tocris Bioscience™ XD 14

Catalog No. 548910
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

BET bromodomain inhibitor

BET bromodomain inhibitor (Kd values are 160, 170, 380, 490, 830 and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2) respectively). Also inhibits BRDT(1), CBP, p300 and BRDT(2) (Kd values are 1.2, 1.6, 2.6 and 3.7 μM respectively). Attenuates proliferation of HL-60 leukemia cells in vitro.

Specifications

Chemical Name or Material XD 14
CAS 1370888-71-3
Synonym 4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 100mM in ethanol
Molecular Formula C20H27N3O5S
Formula Weight 421.51
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use

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