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R&D Systems Zosuquidar Trihydrochloride, Tocris™

High affinity P-glycoprotein (P-gp) inhibitor

Manufacturer:  R&D Systems 5456/10

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Catalog No. 545610

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Research Use Only. Not For Human or Veterinary Use



  • Restores doxorubicin sensitivity in P-gp-expressing multidrug (MDR) resistant cancer cell lines
  • Also potentiates antitumor efficacy of taxol in a MDR human non-small cell lung carcinoma xenograft mouse
Description & Specifications


Zosuquidar trihydrochloride
(αR)-4-[(1aα,6α,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-1-piperazineethanol trihydrochloride
Soluble to 50mM in DMSO
Bioactive Small Molecules

Safety and Handling

Recommended Storage : Store at -20°C.

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