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Invitrogen™ RAB11A Monoclonal Antibody (1565CT164.36.80)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA537686
Description
RAB11A Monoclonal Antibody for Western Blot, IHC (P)
Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.
Specifications
RAB11A | |
Monoclonal | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.4 | |
P62491, P62492, P62494 | |
RAB11A | |
purified recombinant protein of human RAB11A. | |
200 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG1 κ |
Immunohistochemistry (Paraffin), Western Blot | |
1565CT164.36.80 | |
Unconjugated | |
RAB11A | |
24KG; RAB 11A, member oncogene family; RAB11; rab-11; rab11 GTP-binding protein; Rab11a; RAB11a, member RAS oncogene family; ras-related protein Rab-11A; tubulovesicle-associated protein; YL8 | |
Mouse | |
Protein G | |
RUO | |
53869, 81830, 8766 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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