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Invitrogen™ RAB11A Monoclonal Antibody (1565CT164.36.80)
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Catalog No. PIMA537686
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200 μL
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PIMA537686 200 μL
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Catalog No. PIMA537686 Supplier Invitrogen™ Supplier No. MA537686
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Description

Mouse Monoclonal Antibody

RAB11A Monoclonal Antibody for IHC (P), Western Blot

Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB11A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1565CT164.36.80
Concentration 0.48 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene RAB11A
Gene Accession No. P62491, P62492, P62494
Gene Alias 24KG; RAB 11A, member oncogene family; RAB11; rab-11; rab11 GTP-binding protein; Rab11a; RAB11a, member RAS oncogene family; ras-related protein Rab-11A; tubulovesicle-associated protein; YL8
Gene Symbols RAB11A
Host Species Mouse
Immunogen purified recombinant protein of human RAB11A.
Purification Method Protein G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53869, 81830, 8766
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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