Invitrogen™ RAB11A Monoclonal Antibody (7C10)

Catalog No.	Quantity
PIMA124919	100 μg

Catalog No. PIMA124919 Supplier Invitrogen™ Supplier No. MA124919

Description

Mouse Monoclonal Antibody

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.

Specifications

• Antigen: RAB11A
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 7C10
• Concentration: 1.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: RAB11A
• Gene Accession No.: P62491
• Gene Alias: 24KG; RAB 11A, member oncogene family; RAB11; rab-11; rab11 GTP-binding protein; Rab11a; RAB11a, member RAS oncogene family; ras-related protein Rab-11A; tubulovesicle-associated protein; YL8
• Gene Symbols: RAB11A
• Host Species: Mouse
• Immunogen: Rab11a peptide KQMSDRRENDM.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8766
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1