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Invitrogen™ RAB11A/RAB11B Polyclonal Antibody
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Catalog No. PIPA5143391
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100 μL
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PIPA5143391 100 μL
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Catalog No. PIPA5143391 Supplier Invitrogen™ Supplier No. PA5143391
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Description

Rabbit Polyclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB11A/RAB11B
Applications Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Gene RAB11A
Gene Accession No. 0
Gene Alias A730055L17Rik; GTP-binding protein YPT3; H-YPT3; RAB 11A, member oncogene family; RAB11; rab-11; RAB11A; RAB11A, member RAS oncogene family; RAB11B; RAB11B, member of RAS oncogene family; RAB11B, member RAS oncogene family; RAS oncogene family protein; ras-related protein Rab-11A; Ras-related protein Rab-11B; YL8; YPT3
Gene Symbols RAB11A
Host Species Rabbit
Immunogen The immunogen used to generate this antibody corresponds to zebrafish Rab11a + Rab11b.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 436828, 492487
Target Species Zebrafish
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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