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Invitrogen™ RAB11A/RAB11B Polyclonal Antibody
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Catalog No. PIPA5120704
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100 μL
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PIPA5120704 100 μL
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Catalog No. PIPA5120704 Supplier Invitrogen™ Supplier No. PA5120704
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Description

Rabbit Polyclonal Antibody

Positive test controls include: A-549, Mouse brain, Mouse heart, Rat liver, Rat heart. Immunogen sequence: MGTRDDEYDY LFKVVLIGDS GVGKSNLLSR FTRNEFNLES KSTIGVEFAT RSIQVDGKTI KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE.

Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB11A/RAB11B
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Rab11b
Gene Accession No. O35509, P46638, P62491, P62492, P62494, Q15907
Gene Alias A730055L17Rik; GTP-binding protein YPT3; H-YPT3; RAB 11A, member oncogene family; RAB11; rab-11; RAB11A; RAB11A, member RAS oncogene family; RAB11B; RAB11B, member of RAS oncogene family; RAB11B, member RAS oncogene family; RAS oncogene family protein; ras-related protein Rab-11A; Ras-related protein Rab-11B; YL8; YPT3
Gene Symbols RAB11A, Rab11b
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19326, 53869, 79434, 81830, 8766, 9230
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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