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RAB11A Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501732781 Shop All Proteintech Group Inc Products
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50-173-2781 150 μL
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Catalog No. 50-173-2781 Supplier Proteintech Group Inc Supplier No. 202291AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody is specific to RAB11A, and has no cross reaction to RAB11B.

Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.

Specifications

Antigen RAB11A
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RAB11A
Gene Accession No. P62491, P62492
Gene Alias Rab 11, RAB11, RAB11A, Ras related protein Rab 11A, YL8
Gene Symbols Rab11a
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53869, 8766
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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