Invitrogen™ RAB11B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531348

Catalog No. PIPA531348

Description

Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS, Mouse brain, PC-12, Rat2. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway.

Specifications

• Antigen: RAB11B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rab11b
• Gene Alias: A730055L17Rik; GTP-binding protein YPT3; H-YPT3; RAB11B; RAB11B, member of RAS oncogene family; RAB11B, member RAS oncogene family; RAS oncogene family protein; ras-related protein Rab-11B; YPT3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19326, 79434, 9230
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.67 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O35509, P46638, Q15907
• Gene Symbols: Rab11b
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 213 of Human RAB11B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov