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Invitrogen™ RAB12 Polyclonal Antibody
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Catalog No. PIPA5100174
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PIPA5100174 100 μL
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Catalog No. PIPA5100174 Supplier Invitrogen™ Supplier No. PA5100174
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RAB12.

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB12
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RAB12
Gene Accession No. P35283, Q6IQ22
Gene Alias 2900054P15Rik; AW555448; C77700; putative Ras-related protein Rab-12; Rab12; RAB12, member RAS oncogene family; rab-13; ras-related protein Rab-12
Gene Symbols RAB12
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAB12(Accession Q6IQ22), corresponding to amino acid residues L210-C244.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19328, 201475
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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