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Invitrogen™ RAB21 Polyclonal Antibody
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Catalog No. PIPA534404
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100 μg
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Catalog No. Quantity
PIPA534404 100 μg
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Catalog No. PIPA534404 Supplier Invitrogen™ Supplier No. PA534404
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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse kidney tissue lysate. PA5-34404 can be used with blocking peptide PEP-1446.

RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the Alpha-tail of endocytosed integrin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB21
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene RAB21
Gene Accession No. P35282, Q6AXT5, Q9UL25
Gene Alias 9630024B22; GTP-binding protein RAB21; KIAA0118; Rab-12; Rab21; RAB21, member RAS oncogene family; ras-related protein Rab-21
Gene Symbols RAB21
Host Species Rabbit
Immunogen A 19 amino acid synthetic peptide near the carboxy terminus of human RAB21.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 216344, 23011, 299799
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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