RAB21 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6837	100 μL

Catalog No. 50-198-6837 Supplier Bioss Supplier No. BS5830R

Description

Rabbit Polyclonal Antibody

RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the Alpha-tail of endocytosed integrin.

Specifications

• Antigen: RAB21
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: RAB21
• Gene Accession No.: Q9UL25
• Gene Alias: 9630024B22; GTP-binding protein RAB21; KIAA0118; Rab-12; RAB21; RAB21, member RAS oncogene family; Ras-related protein Rab-21
• Gene Symbols: RAB21
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human RAB21.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 23011
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG