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Invitrogen™ RAB23 Polyclonal Antibody
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Catalog No. PIPA5115818
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PIPA5115818 100 μL
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Catalog No. PIPA5115818 Supplier Invitrogen™ Supplier No. PA5115818
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RAB23.

The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 23, also known as HSPC137, is a 237 amino acid member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane. Rab 23 is believed to play a role in intracellular protein transportation and signal transduction mediated by small GTPases. Mutations in the gene encoding Rab 23 may result in Carpenter syndrome, also known as ACPS2 (acrocephalopolysyndactyly type 2), a condition characterized by obesity, cardiac defects, polysyndactyly and craniosynostosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB23
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene RAB23
Gene Accession No. P35288, Q9ULC3
Gene Alias AW545388; DKFZp781H0695; HSPC137; MGC8900; opb; opb2; open brain 2; OTTHUMP00000040021; protein open brain; RAB 23; RAB family small GTP binding protein RAB 23; rab-15; RAB23; RAB23, member RAS oncogene family; ras-related protein Rab-23; RP3-496N17.3
Gene Symbols RAB23
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAB23(Accession Q9ULC3), corresponding to amino acid residues E179-N229.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19335, 51715
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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