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Invitrogen™ RAB27A Polyclonal Antibody
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Catalog No. PIPA5102522
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100 μL
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Catalog No. Quantity
PIPA5102522 100 μL
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Catalog No. PIPA5102522 Supplier Invitrogen™ Supplier No. PA5102522
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RAB27A.

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB27A
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RAB27A
Gene Accession No. P23640, P51159, Q9ERI2
Gene Alias 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; ashen; GS2; GTP-binding protein Ram; HsT18676; low Mr GTP-binding protein; mutant Ras-related protein Rab-27A; RAB27; rab-27; Rab27a; RAB27A, member RAS oncogene family; ram; Ram p25; ras-related protein Rab-27A
Gene Symbols RAB27A
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAB27A(Accession P51159), corresponding to amino acid residues E186-C221.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11891, 50645, 5873
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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