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Invitrogen™ RAB27A Polyclonal Antibody
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Catalog No. PIPA579904
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100 μg
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PIPA579904 100 μg
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Catalog No. PIPA579904 Supplier Invitrogen™ Supplier No. PA579904
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human Jurkat whole cell, human MCF-7 whole cell, human HepG2 whole cell, human A549 whole cell, rat stomach tissue, rat thymus tissue, mouse thymus tissue, mouse NIH3T3 whole cell. IHC: human lung cancer tissue, human mammary cancer tissue, rat small intestine tissue, rat spleen tissue, mouse spleen tissue. Flow: K562 cell.

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB27A
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene RAB27A
Gene Accession No. P23640, P51159, Q9ERI2
Gene Alias 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; ashen; GS2; GTP-binding protein Ram; HsT18676; low Mr GTP-binding protein; mutant Ras-related protein Rab-27A; RAB27; rab-27; Rab27a; RAB27A, member RAS oncogene family; ram; Ram p25; ras-related protein Rab-27A
Gene Symbols RAB27A
Host Species Rabbit
Immunogen E. coli-derived human RAB27A recombinant protein (Position: L98-K216).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11891, 50645, 5873
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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