Invitrogen™ RAB27A Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547907

Catalog No. PIPA547907

Description

This antibody detects human, mouse, and rat RAB27A in Western blots and recombinant human RAB27A in direct ELISAs. In direct ELISAs, less than 1% cross-reactivity with recombinant human RAB27B is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.

Specifications

• Antigen: RAB27A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB27A
• Gene Alias: 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; ashen; GS2; GTP-binding protein Ram; HsT18676; low Mr GTP-binding protein; mutant Ras-related protein Rab-27A; RAB27; rab-27; Rab27a; RAB27A, member RAS oncogene family; ram; Ram p25; ras-related protein Rab-27A
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11891, 50645, 5873
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P23640, P51159, Q9ERI2
• Gene Symbols: RAB27A
• Immunogen: E. coli-derived recombinant human RAB27A Ser135-Ala218.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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