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Rab3-GAP1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501561805
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50-156-1805 100 μL
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Catalog No. 50-156-1805 Supplier Bethyl Laboratories, Inc Supplier No. A302114A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Rab 3 GAP p130, also known as Rab3 GTPase-activating protein catalytic subunit, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Specifications

Antigen Rab3-GAP1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene RAB3GAP1
Gene Accession No. Q15042
Gene Alias Rab3 GTPase-activating protein catalytic subunit, RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAP, KIAA0066, RAB3GAP, Rab 3 GAP p130, Rab3 GAP p130
Gene Symbols RAB3GAP1
Host Species Rabbit
Immunogen Between 575 and 625
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22930
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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