Invitrogen™ RAB33A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120525

Catalog No. PIPA5120525

Description

Positive test controls include: Mouse brain, Rat brain. Immunogen sequence: DVTKMTSFTN LKMWIQECNG HAVPPLVPKV LVGNKCDLRE QIQVPSNLAL KFADAHNMLL FETSAKDPKE SQNVESIFMC LACRLKAQKS LLYRDAERQQ GKVQKLEFPQ EANSKTSCPC.

The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 33B and Rab 33A share conserved effector domains, but share only 55.3% overall amino acid identity. This suggests that Rab 33B and Rab 33A may interact with similar effector and regulatory proteins.

Specifications

• Antigen: RAB33A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB33A
• Gene Alias: RAB 33A; Rab33a; RAB33A, member of RAS oncogene family; RAB33A, member RAS oncogene family; Rabs10; Ras-related protein Rab-33A; RGD1563280; small GTP-binding protein S10
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19337, 317580
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.81 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P97950
• Gene Symbols: RAB33A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 118-237 of human RAB33A (NP_004785.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG