Invitrogen™ RAB3C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521963

Catalog No. PIPA521963

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, mouse brain, rat brain. Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (81%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland, and pituitary.

Specifications

• Antigen: RAB3C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB3C
• Gene Alias: 2700062I01Rik; 3110015B08Rik; 3110037E15Rik; AI850886; RAB3C; RAB3C, member RAS oncogene family; ras-related protein Rab-3C; small GTP-binding protein Rab3C
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115827, 171058, 67295
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.94 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P62823, P62824, Q96E17
• Gene Symbols: RAB3C
• Immunogen: Full length human RAB3C Recombinant protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG