Invitrogen™ RAB3d Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587863

Catalog No. PIPA587863

Description

Immunogen sequence: MASAGDTQAG PRDAADQNFD YMFKLLLIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTVYRHDKR IKLQIWDTAG QERYRTITTA YYRGAMGFLL MYDIANQESF AAVQDWATQI KTYSWDNAQV ILVGNKCDLE DERVVPAEDG RRLADDLGFE FFEASAKENI NVKQVFERLV DVICEKMNES LEPSSSSGSN GKGPAVGDAP APQPSSCSC; Positive Samples: HepG2, U-87MG, MCF7, SKOV3, Mouse lung, Mouse pancreas; Cellular Location: Cell membrane, Cytoplasmic side, Lipid-anchor.

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals. Rab 3D has been shown to be present, in part, in the tongue, pancreas, and liver.

Specifications

• Antigen: RAB3d
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rab3d
• Gene Alias: C130057E11Rik; D2-2; glioblastoma overexpressed; GOV; GTP-binding protein Rab-3D; RAB16; Rab3d; Rab3D upregulated with myeloid differentiation; RAB3D, member RAS oncogene family; RAD3D; Ras-related protein Rab-3D
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19340, 9545
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.94 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95716, P35276
• Gene Symbols: Rab3d
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human RAB3D (NP_0042741).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG