Invitrogen™ RAB3GAP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101803

Catalog No. PIPA5101803

Description

Antibody detects endogenous levels of total RAB3GAP1.

RAB3GAP1, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Specifications

• Antigen: RAB3GAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB3GAP1
• Gene Alias: 1700003B17Rik; 4732493F09Rik; AL117896; KIAA0066; P130; Rab 3 GAP p130; Rab3 GAP p130; RAB3 GTPase activating protein catalytic subunit 1; RAB3 GTPase activating protein subunit 1; RAB3 GTPase activating protein subunit 1 (catalytic); RAB3 GTPase-activating protein 130 kDa subunit; Rab3 GTPase-activating protein catalytic subunit; RAB3GAP; Rab3-GAP; Rab3-GAP p130; Rab3gap1; RAB3GAP130; RGD1306487; WARBM1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 226407, 22930
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q15042, Q80UJ7
• Gene Symbols: RAB3GAP1
• Immunogen: A synthesized peptide derived from human RAB3GAP1(Accession Q15042), corresponding to amino acid residues S537-E587.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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