Invitrogen™ RAB3GAP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556952

Catalog No. PIPA556952

Description

Immunogen sequence: PISELHLATT WPHLTEGIIV DNDVYSDLDP IQAPHWSVRV RKAENPQCLL GDFVTEFFKI CRRKESTDEI LGRSAFEEEG KETADITHAL SK Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.

RAB3GAP1, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Specifications

• Antigen: RAB3GAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB3GAP1
• Gene Alias: 1700003B17Rik; 4732493F09Rik; AL117896; KIAA0066; P130; Rab 3 GAP p130; Rab3 GAP p130; RAB3 GTPase activating protein catalytic subunit 1; RAB3 GTPase activating protein subunit 1; RAB3 GTPase activating protein subunit 1 (catalytic); RAB3 GTPase-activating protein 130 kDa subunit; Rab3 GTPase-activating protein catalytic subunit; RAB3GAP; Rab3-GAP; Rab3-GAP p130; Rab3gap1; RAB3GAP130; RGD1306487; WARBM1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22930
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15042
• Gene Symbols: RAB3GAP1
• Immunogen: Recombinant protein corresponding to Human RAB3GAP1. Recombinant protein control fragment (Product #RP-102619).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov