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Invitrogen™ RAB3IP Polyclonal Antibody
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Catalog No. PIPA544020
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100 μL
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PIPA544020 100 μL
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Catalog No. PIPA544020 Supplier Invitrogen™ Supplier No. PA544020
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Description

Rabbit Polyclonal Antibody

Peptide sequence: SPDLLGVYES GTQEQTTSPS VIYRPHPSAL SSVPIQANAL DVSELPTQPV Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 91%; Human: 100%; Mouse: 79%; Rabbit: 92%; Rat: 93%.

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB3IP
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene RAB3IP
Gene Accession No. Q68EF0, Q96QF0
Gene Alias B230311A06; gene trap PAT 12; Gtpat12; MGC137223 protein; RAB3A interacting protein; RAB3A interacting protein (rabin3); rab-3A-interacting protein; RAB3A-interacting protein; RAB3IP; rab3ip {ECO:0000250; rabin 3; Rabin3; rabin-3; RABIN8; SSX2 interacting protein; SSX2-interacting protein; UniProtKB:Q96QF0}
Gene Symbols RAB3IP
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human RAB3IP (aa 35-84).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117177, 216363
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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