Invitrogen™ RAB3IP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588659

Catalog No. PIPA588659

Description

Immunogen sequence: MANDPLEGFH EVNLASPTSP DLLGVYESGT QEQTTSPSVI YRPHPSALSS VPIQANALDV SELPTQPVYS SPRRLNCAEI SSISFHVTDP APCSTSGVTA GLTKLTTRKD NYNAEREFLQ GATITEACDG SDDIFGLSTD SLSRLRSPSV; Positive Samples: 293T; Cellular Location: Cell projection, Cytoplasm, Nucleus, cytoskeleton, lamellipodium.

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

Specifications

• Antigen: RAB3IP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB3IP
• Gene Alias: B230311A06; gene trap PAT 12; Gtpat12; MGC137223 protein; RAB3A interacting protein; RAB3A interacting protein (rabin3); rab-3A-interacting protein; RAB3A-interacting protein; RAB3IP; rab3ip {ECO:0000250; rabin 3; Rabin3; rabin-3; RABIN8; SSX2 interacting protein; SSX2-interacting protein; UniProtKB:Q96QF0}
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117177, 216363, 29885
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q62739, Q68EF0, Q96QF0
• Gene Symbols: RAB3IP
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RAB3IP (NP_0719012).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG