Invitrogen™ RAB40B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536509

Catalog No. PIPA536509

Description

This antibody detects endogenous protein at a molecular weight of 34 kDa. Purity is >95% by SDS-PAGE.

Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family. Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles. The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3. It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.

Specifications

• Antigen: RAB40B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rab40b
• Gene Alias: GTP-binding protein homologous to Saccharomyces cerevisiae SEC4; protein Rar; RAB40B; Rab40b, member RAS oncogene family; rar; RAR SOCS box containing protein; ras-related protein Rab-40B; sec4; SEC4L; SOCS box-containing protein RAR
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10966, 217371, 303754
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q12829, Q8VHP8
• Gene Symbols: Rab40b
• Immunogen: Synthetic peptide corresponding to amino acids 231-278 of Human Rab 40B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG