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Invitrogen™ RAB40B Polyclonal Antibody
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Catalog No. PIPA5106719
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100 μL
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PIPA5106719 100 μL
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Catalog No. PIPA5106719 Supplier Invitrogen™ Supplier No. PA5106719
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RAB40B.

Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family. Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles. The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3. It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB40B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Rab40b
Gene Accession No. Q12829, Q8VHP8
Gene Alias GTP-binding protein homologous to Saccharomyces cerevisiae SEC4; protein Rar; RAB40B; Rab40b, member RAS oncogene family; rar; RAR SOCS box containing protein; ras-related protein Rab-40B; sec4; SEC4L; SOCS box-containing protein RAR
Gene Symbols Rab40b
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAB40B(Accession Q12829), corresponding to amino acid residues R234-S278.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10966, 217371, 303754
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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