Invitrogen™ RAB40B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106719

Catalog No. PIPA5106719

Description

Antibody detects endogenous levels of total RAB40B.

Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family. Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles. The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3. It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.

Specifications

• Antigen: RAB40B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rab40b
• Gene Alias: GTP-binding protein homologous to Saccharomyces cerevisiae SEC4; protein Rar; RAB40B; Rab40b, member RAS oncogene family; rar; RAR SOCS box containing protein; ras-related protein Rab-40B; sec4; SEC4L; SOCS box-containing protein RAR
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10966, 217371, 303754
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q12829, Q8VHP8
• Gene Symbols: Rab40b
• Immunogen: A synthesized peptide derived from human RAB40B(Accession Q12829), corresponding to amino acid residues R234-S278.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov