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Invitrogen™ RAB40B Polyclonal Antibody
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Catalog No. PIPA5140185
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100 μL
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PIPA5140185 100 μL
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Catalog No. PIPA5140185 Supplier Invitrogen™ Supplier No. PA5140185
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: SLQDLCCRAV VSCTPVHLVD KLPL Highest antigen sequence indentity to the following orthologs: Mouse - 92%, Rat - 100%.

Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family. Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles. The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3. It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB40B
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Rab40b
Gene Accession No. Q12829
Gene Alias GTP-binding protein homologous to Saccharomyces cerevisiae SEC4; protein Rar; RAB40B; Rab40b, member RAS oncogene family; rar; RAR SOCS box containing protein; ras-related protein Rab-40B; sec4; SEC4L; SOCS box-containing protein RAR
Gene Symbols Rab40b
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RAB40B. Recombinant protein control fragment (Product #RP-109539).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10966
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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