RAB43 Mouse anti-Human, Clone: 3B2A8, Proteintech

Catalog No.	Quantity
50-173-7072	150 μL

Catalog No. 50-173-7072 Supplier Proteintech Group Inc Supplier No. 666541IG150UL

Description

Mouse Monoclonal Antibody

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Specifications

• Antigen: RAB43
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 3B2A8
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: RAB43
• Gene Accession No.: Q86YS6
• Gene Alias: ISY1, RAB11B, RAB41, RAB43, Ras related protein Rab 41, Ras related protein Rab 43
• Gene Symbols: RAB43
• Host Species: Mouse
• Immunogen: RAB43 Fusion Protein Ag26911
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 339122
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1