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RAB43 Mouse anti-Human, Clone: 3B2A8, Proteintech
SDP

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 666541IG150UL

Encompass_Preferred

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Catalog No. 50-173-7072


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Description

Description

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
Specifications

Specifications

RAB43
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q86YS6
RAB43
RAB43 Fusion Protein Ag26911
150 μL
Primary
Human
Antibody
IgG1
Western Blot
3B2A8
Unconjugated
RAB43
ISY1, RAB11B, RAB41, RAB43, Ras related protein Rab 41, Ras related protein Rab 43
Mouse
Protein G
RUO
339122
-20°C
Liquid
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