RAB43 Mouse anti-Human, Clone: 3B2A8, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 666541IG150UL

Catalog No. 50-173-7072

Description

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Specifications

• Antigen: RAB43
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q86YS6
• Gene Symbols: RAB43
• Immunogen: RAB43 Fusion Protein Ag26911
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 3B2A8
• Conjugate: Unconjugated
• Gene: RAB43
• Gene Alias: ISY1, RAB11B, RAB41, RAB43, Ras related protein Rab 41, Ras related protein Rab 43
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 339122
• Content And Storage: -20°C
• Form: Liquid