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RAB5A Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501732780 Shop All Proteintech Group Inc Products
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50-173-2780 150 μL
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Catalog No. 50-173-2780 Supplier Proteintech Group Inc Supplier No. 202281AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody is specific to RAB5A. It has no cross reaction to RAB5B or RAB5C.

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.

Specifications

Antigen RAB5A
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RAB5A
Gene Accession No. P20339, Q9CQD1
Gene Alias RAB5, RAB5A, Ras related protein Rab 5A
Gene Symbols Rab5a
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 271457, 5868
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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