Invitrogen™ RAB7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552369

Catalog No. PIPA552369

Description

Immunogen sequence: CVLVFDVTAP NTFKTLDSWR DEFLIQASPR DPENFPFVVL GNKIDLENRQ VATKRAQAWC YSKNNIPYFE TSAKEAINVE QAFQTIARNA LKQETEVELY NEFPEPIKLD KNDRAK Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

Specifications

• Antigen: RAB7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB7A
• Gene Alias: GTP-binding protein (rab7); hypothetical protein LOC509970; PRO2706; RAB7; rab-7; RAB7, member RAS oncogene family; Rab7a; RAB7A, member RAS oncogene family; Ras-associated protein RAB7; ras-related protein BRL-RAS; Ras-related protein p23; ras-related protein Rab-7a
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 110315128, 19349, 29448, 7879
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.20 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P09527, P51149, P51150
• Gene Symbols: Rab7, RAB7A
• Immunogen: Recombinant protein corresponding to Human RAB7. Recombinant protein control fragment (Product #RP-89503).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov