Invitrogen™ RAB7A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109239

Catalog No. PIPA5109239

Description

Positive Control: MCF-7, A431, SiHa, rat brain tissue, human tonsil tissue, human liver tissue, human colon cancer tissue, mouse colon tissue.

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

Specifications

• Antigen: RAB7A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB7A
• Gene Alias: GTP-binding protein (rab7); hypothetical protein LOC509970; PRO2706; RAB7; rab-7; RAB7, member RAS oncogene family; Rab7a; RAB7A, member RAS oncogene family; Ras-associated protein RAB7; ras-related protein BRL-RAS; Ras-related protein p23; ras-related protein Rab-7a
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7879
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P51149
• Gene Symbols: RAB7A
• Immunogen: Recombinant protein within Human RAB7 aa 43-200.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov