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Invitrogen™ RAB7A Recombinant Rabbit Monoclonal Antibody (SN202-03)
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Catalog No. PIMA532340
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PIMA532340 100 μL
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Catalog No. PIMA532340 Supplier Invitrogen™ Supplier No. MA532340
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Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
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Specifications

Antigen RAB7A
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone SN202-03
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene RAB7A
Gene Accession No. P09527, P51149, P51150
Gene Alias GTP-binding protein (rab7); hypothetical protein LOC509970; PRO2706; RAB7; rab-7; RAB7, member RAS oncogene family; Rab7a; RAB7A, member RAS oncogene family; Ras-associated protein RAB7; ras-related protein BRL-RAS; Ras-related protein p23; ras-related protein Rab-7a
Gene Symbols Rab7, RAB7A
Host Species Rabbit
Immunogen Synthetic peptide within Human RAB7 aa 158-207.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110315128, 19349, 29448, 7879
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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