Invitrogen™ RAB8A Monoclonal Antibody (261CT1.3.1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524717

Catalog No. PIMA524717

Description

RAB8A Monoclonal Antibody for Western Blot

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Specifications

• Antigen: RAB8A
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P55258, P61006
• Gene Symbols: RAB8A
• Immunogen: human RAB8A recombinant protein.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: 261CT1.3.1
• Conjugate: Unconjugated
• Gene: RAB8A
• Gene Alias: AA409338; cell line NK14 derived transforming oncogene; MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; Rab8; Rab8a; RAB8A, member RAS oncogene family; ras-associated protein RAB8; ras-related protein Rab-8A
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 17274, 4218
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid