Invitrogen™ RAB8B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537209

Catalog No. PIPA537209

Description

This antibody detects endogenous protein at a molecular weight of 42 kDa. Purity is >95% by SDS-PAGE.

The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. Rab 8B (Ras-related protein Rab-8B) is a 207 amino acid lipid anchor that localizes to the cytoplasmic side of the cell membrane and belongs to the Rab family and small GTPase superfamily. Rab 8B may be involved in neurotransmitter release and vesicular trafficking, and is encoded by a gene located on human chromosome Rab 8B and mouse chromosome 9 C.

Specifications

• Antigen: RAB8B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB8B
• Gene Alias: 5930437D16; D330025I23Rik; FLJ38125; GTPase Rab8b; LOW QUALITY PROTEIN: ras-related protein Rab-8B; RAB44, member RAS oncogene family; RAB8B; RAB-8b protein; RAB8B, member RAS oncogene family; rab8bb; ras-related protein Rab-8B; ras-related protein Rab-8B; LOW QUALITY PROTEIN: ras-related protein Rab-8B; Ras-related protein Rab-8B-like protein; Unknown (protein for MGC:127591); zgc:165529
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 235442, 266688, 51762
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P61028, P70550, Q92930
• Gene Symbols: RAB8B
• Immunogen: A synthetic peptide corresponding to residues in human RAB8B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov