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Invitrogen™ RAB9 Polyclonal Antibody
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Catalog No. PIPA5101027
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PIPA5101027 100 μL
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Catalog No. PIPA5101027 Supplier Invitrogen™ Supplier No. PA5101027
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Rab9.

Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport. Different members of the 40+ member rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell. Rab 9 is required for trafficking mannose 6-phosphate receptor between the late endosome to trans-Golgi network (TGN). By facilitating receptor transport, rab 9 enables cells to efficiently recycle important cellular trafficking components. It is functionally necessary for rab 9, like other rab family members, to be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus. Most prenylated rab 9 is membrane bound, however, 10-20% of the cellular pool of rab 9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol. GDI recycles prenylated, GDP bound rab 9 from their fusion targets back to their membranes of origin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB9
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Rab9a
Gene Accession No. P51151, Q99P75, Q9R0M6
Gene Alias 2410064E05Rik; AI195561; rab9; rab9 GTP-binding protein; RAB9, member RAS oncogene family; Rab9a; rab-9A; RAB9A, member RAS oncogene family; RAB9-like protein; ras-related protein Rab-9A; Sid 99; Sid6061p; Sid99
Gene Symbols Rab9, Rab9a
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAB9A(Accession P51151), corresponding to amino acid residues L72-L122.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56382, 84589, 9367
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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