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AANAT, Rabbit, DyLight 549, Polyclonal Antibody, Abnova™

Catalog No. 89117414 Shop All Abnova Corporation Products
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89-117-414 100 μL
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Catalog No. 89-117-414 Supplier Abnova Corporation Supplier No. PAB15048

Rabbit polyclonal antibody raised against AANAT.

Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle. [provided by RefSeq

Specifications

Antigen AANAT
Applications Immunocytochemistry, Western Blot
Classification Polyclonal
Conjugate DyLight 549
Description Rabbit polyclonal antibody raised against AANAT.
Dilution Western Blot (1:500-1:1000) Immunocytochemistry (1:200) The optimal working dilution should be determined by the end user.
Formulation In 50mM sodium borate
Gene AANAT
Gene Accession No. U40347
Gene Alias AA-NAT/SNAT
Gene Symbols AANAT
Host Species Rabbit
Immunogen Human AANAT.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15
Test Specificity Recognizes human and rhesus AANAT. It does not recognize rat, ovine, chicken or zebrafish AANAT. This is specific to primate AANAT (3,4). By Western blot, this antibody recognizes a band at 23 KDa representing hAANAT.
Target Species Human, Primate
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
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For Research Use Only

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