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ABCB1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89118379 Shop All Abnova Corporation Products
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50 μg
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89-118-379 50 μg
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Catalog No. 89-118-379 Supplier Abnova Corporation Supplier No. PAB16508
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Description

Rabbit polyclonal antibody raised against synthetic peptide of ABCB1.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq

Specifications

Antigen ABCB1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ABCB1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene ABCB1
Gene Accession No. P08183
Gene Alias ABC20/CD243/CLCS/GP170/MDR1/MGC163296/P-GP/PGY1
Gene Symbols ABCB1
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human ABCB1.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5243
Test Specificity Cytoplasmic domain of human.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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