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Description
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | ABCE1 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of ABCE1. |
| Dilution | ELISA (1:160000) Western Blot (1:1000-1:2000) The optimal working dilution should be determined by the end user. |
| Formulation | In buffer containing 0.02% sodium azide |
| Gene | ABCE1 |
| Gene Accession No. | P61221 |
| Gene Alias | ABC38/OABP/RLI/RNASEL1/RNASELI/RNS4I |
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