ABCG8 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of ABCG8.
Manufacturer: Abnova Corporation PAB12502
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude noncholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq
|Western Blot (1:250) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to N-terminus of human ABCG8.|
|Rabbit polyclonal antibody raised against synthetic peptide of ABCG8.|
|In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)|
|Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody is specific to human ABCG8.|
For Research Use Only