ABCG8 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ABCG8.

Supplier:  Abnova Corporation PAB18824

Catalog No. 89-120-383

Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude noncholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq

Specifications

• Antigen: ABCG8
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ABCG8.
• Formulation: In buffer containing 0.02% sodium azide
• Gene Accession No.: Q9H221
• Gene Symbols: ABCG8
• Immunogen: A synthetic peptide corresponding to amino acids at C-terminus of human ABCG8.
• Regulatory Status: RUO
• Gene ID (Entrez): 64241
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:160000) Western Blot (1:1000-1:2000) The optimal working dilution should be determined by the end user.
• Gene: ABCG8
• Gene Alias: GBD4/MGC142217/STSL
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only