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ACACA Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89118943 Shop All Abnova Corporation Products
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100 μg
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89-118-943 100 μg
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Catalog No. 89-118-943 Supplier Abnova Corporation Supplier No. PAB17278
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Description

Rabbit polyclonal antibody raised against synthetic peptide of ACACA.

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Specifications

Antigen ACACA
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ACACA.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Gene ACACA
Gene Accession No. Q13085
Gene Alias ACAC/ACC/ACC1/ACCA
Gene Symbols ACACA
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues surrounding serine 80 of human ACACA.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 31
Test Specificity This antibody detects endogenous levels of total ACACA Carboxylase protein.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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